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KMID : 0376219780150010009
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Chonnam Medical Journal
1978 Volume.15 No. 1 p.9 ~ p.19
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Noninvasive Evaluation of Cardiac Function and Hemodynamics correlated with Serum Thyroxine in Hyperthyroidism
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Abstract
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Systolic time intervals and hemodynamics were determined from simultaneous records of the electrocardiogram, carotid arterial pulse, femoral arterial. pulse and phonocardiogram in sixteen patients with simple goiter and thirty-six patients with hype rthyroidism.
Systolic time intervals and hemodynamics in hyperthyroidism and simple goiter appeared to be relevant with serum thyroxine level.
Systolic time intervals in hyperthyroidism were characterized by reduction of pre-ejection period, left ventricular ejection time and electromechanical systole with a resultant decrease in the PEP/ LVET ratio and with a resultant increase in the LVET/PEP ratio.
The pre-ejection period and electromechanical systole correcting for heart rate in hyperthyroidism were shortened significantly whill the left ventricular ejection time correcting for heart rate remained unaltered.
The reduction of pre-ejection period, pre-ejection period correcting for heart rate, left. ventricular ejection time, electromechanical systole and electromechanical systole correcting for heart rate were inversely correlated with serum thygxine level while. the left ventricular ejection time correcting for heart rate was. not related with serum thyroxine level. The reduction in PEP/LVET ratio and the elevation in LVET/PEP ratio were well related to serum thyroxine level.
In hyperthyroidism, the heart rate, cardiac output and coefficiency of volume elasticity were elevated remarkably, which were closely associated with serum thyroxine level, but only the stroke volume remained unaltered.
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